Trish,if you are interested,
An
athlete biological passport is an individual, electronic record for professional athletes, in which profiles of
biological markers of doping and results of
doping tests are collated over a period of time. Doping violations can be detected by noting variances from an athlete’s established levels outside permissible limits, rather than testing for and identifying
illegal substances.
[1]
Although the terminology
athlete passport is recent, the use of biological markers of doping has a long history in anti-doping. Maybe the first marker of doping, that tries to detect a prohibited substance not based on its presence in urine or blood, but through the induced deviations in biological parameters, is the so-called testosterone over epitestosterone ratio (T/E). The T/E has been used by sports authorities since the beginning of the 1980s to detect
anabolic steroids in urine samples. A decade later, in 1997, markers of blood doping were introduced by some international federations, such as the
Union Cycliste Internationale and the
Federation Internationale de Ski, to deter the abuse of recombinant
erythropoietin that was undetectable by direct means at that time. It is only in 2002 that the paradigm to use biological markers of doping took the terminology
athlete passport. The merits of this testing paradigm were exposed in the scientific literature
[2] and the terminology adopted by the World Anti-Doping agency.
[3]
Many believe[
who?] that the
athlete passport provides an excellent alternative to ensure fairness in elite sports. While a new
drug test must be developed and validated for each new drug, the main advantage of the
athlete passport is that it is based on the stability of the physiology of the human being. New drugs are produced at an unprecedented pace today and there is often a lag of several years between the availability of a new drug and the application of an effective detection method. On the contrary, the physiology of the human being remains the same through several generations and all
biomarkers developed today in the
athlete passport will remain valid for at least several decades.
For example, the blood module of the passport is already sensitive today to any new future form of recombinant erythropoietin, as well as to any form of gene doping that will enhance oxygen transfer to the muscles. Also, while a negative
drug test does not necessarily mean that the athlete did not dope, the athlete can present his/her passport at the beginning of a competition to attest that he/she will compete in his/her natural, unaltered condition.
The
athlete passport has received a lot of attention when its blood module was established at the beginning of the 2008 racing season by the
Union Cycliste Internationale.
[4] In May 2008 the UCI revealed that 23 riders were under suspicion of doping following the first phase of blood tests conducted under the new biological passport.
[5] The blood module of the
athlete passport aims to detect any form of
blood doping, the steroid module any form of doping with
anabolic steroid and the endocrine module any modification of the
growth hormone/
IGF-1 axis. Each of these modules are however at different steps of development, validation and application in sports.